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About Kibow Therapeutics

Dedicated to Helping Patients with Chronic Kidney Disease

We are advancing potential first-in-class live biotherapeutics for CKD and ESRD.

Kibow Therapeutics is a clinical-stage developer of live biotherapeutics for persons with chronic kidney disease (CKD). The Company is advancing potential first-in-class therapies to selectively modulate the gut microbiome to improve kidney function and quality of life. Kibow Therapeutics is focused first on KT-301, an encapsulated consortium of proprietary strains of commensal bacteria targeting uremic toxins associated with CKD. Phase 2 clinical studies in CKD patients are underway to assess KT-301’s safety and its ability to halt or slow progression of CKD. A Phase 2 study in end-stage renal disease (ESRD) patients undergoing dialysis is also planned. Kibow Biotech is a wholly owned subsidiary of Kibow Therapeutics. For more than 25 years Kibow Biotech has built a leadership position in probiotic research and development, with a number of commercialized products, led by Renadyl™ for the maintenance of renal health. Kibow Therapeutics is headquartered in Newtown Square, PA.

Kibow Means Hope

Our Heritage

Kibow Biotech, a wholly owned subsidiary of Kibow Therapeutics, is a leader in probiotic research and development with commercialized products including Renadyl.

Now in its 25th year, Kibow Biotech is a leading source of scientifically formulated probiotic/prebiotic dietary supplements. Guided by its leadership and a group of internationally recognized scientific advisors, Kibow Biotech has accomplished pharmaceutical-like development and validation for its proprietary probiotic/prebiotic formulations for kidney health and general wellness purposes. Kibow Biotech has been awarded highly competitive Small Business Innovation Research (SBIR) Grant Awards from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK-NIH) and Qualifying Therapeutic Discovery Project (QTDP) Programs. Additionally, Kibow Biotech has secured USAID grant funding for R&D and product development.

Kibow Biotech is a leader provider of probiotic dietary supplements for kidney health, marketed under the brand name Renadyl™.


Our leadership team includes creative, resourceful, and well-connected life sciences industry veterans. In addition, we bring 25 years of operating experience as a developer of live biotherapeutics across multiple domains, with a focus on kidney health.

Robert Segal, M.D.

Medical / Scientific Advisor

We Strive to Improve Outcomes with Our Novel Adjunctive CKD Therapies

Chronic kidney disease (CKD) is characterized by a gradual loss of kidney function. As many as one in nine U.S. adults has CKD. Kibow Therapeutics is advancing novel, non-invasive therapies to improve quality of life and slow the progression of CKD.

Robert Segal, M.D., F.A.C.P.

Medical / Scientific Advisor

Dr. Segal has over 30 years of life sciences industry experience including in the design, conduct, and execution of numerous multi-national, multi-site clinical programs and non-clinical studies. Dr. Segal previously served as Chief Medical Officer at Discovery Laboratories (now Windtree Therapeutics), where, in addition to serving as executive management, he focused on many successful Federal funding opportunities, including important biodefense initiatives. Dr. Segal has received well in excess of $10 million in NIH awards to evaluate novel drug and drug-device combination therapies. Previously, at Merck he held the position of Director, Cardiovascular Clinical Research where he was a key contributor to the approval and launch of Cozaar® (losartan). Prior to joining Merck, he was an Assistant Professor of Medicine in the Division of Nephrology / Transplantation at University of California, Los Angeles School of Medicine and served as an advisor to the Biotechnology Program at Northwestern University. Dr. Segal received his medical degree from the University of Pretoria Medical School, South Africa.


Graham Lumsden, BVM&S, DipM, MRCVS


Dr. Lumsden is a Director of Kibow Therapeutics. Prior to joining Kibow, he was President and CEO of Biomarck Pharmaceuticals, a clinical stage biotechnology company focused on treating patients with inflammatory and immunological diseases. Prior to Biomarck, Dr. Lumsden was CEO of Motif Bio, where he raised $125 million and led two IPOs (AIM and NASDAQ) to advance iclaprim, a targeted antibacterial, through Phase 3 and NDA submission. Dr. Lumsden previously founded and was the CEO of Tiemed LLC, a biotech company developing solutions for patients with difficulties taking oral medicines. Dr. Lumsden spent more than twenty years at Merck & Co., where he gained global experience in both the veterinary and human health markets. Dr. Lumsden received his Bachelor of Veterinary Medicine & Surgery from University of Edinburgh and his Postgraduate Diploma in Marketing from the Chartered Institute of Marketing in the U.K.


Greg Bosch, M.B.A.


Mr. Bosch brings over 30 years in healthcare to Panavance, a company focused on improving the effectiveness of cancer treatments, with leadership of commercial, operations, and R&D teams in the U.S. and Europe. His general management experience in the life science industry spans the pharmaceutical, biologics and medical device segments including building a biosurgery business to $220M in five years, acquiring public and private companies, and taking a company public. Prior to joining Panavance, Greg was Chief Executive Officer of Geistlich Pharma North America, where he led a cross functional team to achieve the market leadership position in regenerative medicine in the U.S. dental field. Greg earned his B.A. in Public Policy from Duke University and MBA from DePaul University.


Steve Kirton


Mr. Kirton is the founder and CEO of Circa Healthcare, a strategic healthcare communications agency. During his 11-year tenure with an international medical diagnostics company based in the UK, Mr. Kirton rose from Sales Representative to Director of International Sales and Marketing. He then moved to the U.S. and held a role as Business Unit Manager for Centocor, a leading biopharmaceutical company. His corporate experience was followed by several years as an ad agency executive, not only at his own company, but also at New York-based Euro RSCG Life.


Natarajan Ranganathan, Ph.D.

Founder, In Memoriam

Dr. Ranganathan dedicated his life to treating chronic kidney disease and was the visionary founder of Kibow Biotech. For more than twenty years,  Dr. Ranganathan provided scientific leadership to optimally deploy probiotics and prebiotics across a variety of use cases. Under his guidance, Kibow Biotech flourished as a scientifically-backed provider of high quality over the counter products. Dr. Ranganathan obtained his Ph.D. in bio-organic chemistry from Temple University. He received further academic training at the University of Pennsylvania and at and Johns Hopkins University. Beyond his professional accomplishments, he was a committed philanthropist and an active and cherished member of his community.